3/30/2023 0 Comments Charcot marie tooth disease mtmr![]() ![]() Some types of CMT affect both the axon and the myelin sheath. In other cases, the condition affects one of the parts that make up your nerve cells, the axon. Most commonly, CMT affects the protective sheath that coats your nerves, called myelin. The CMT-causing genes can cause problems with different parts of the peripheral nerves. These people will develop CMT, and they can also pass down the CMT-causing genes to their children. ![]() In some rare cases, people are born with the genes that cause CMT spontaneously, without inheriting them from their parents. And if you later have children, you can pass these CMT-causing genes to your own children. In most cases, you inherit the problem genes, known as mutated genes, from one or both of your parents. The condition is caused by problems with one or more of your genes. This means it’s present at birth, even though the symptoms of CMT often don’t appear until you’re in your teenage years or older. Treatments, therapies, and supportive devices can help you to manage most symptoms.ĬMT is a congenital disease. Mild to moderate loss of sensation in your limbs is also common. Many CMT symptoms can differ from person to person, but everyone with CMT will eventually develop muscle weakness and wasting in the limbs, reduced reflexes, and skeletal changes. This can affect your fine motor skills, your mobility, and in some cases, your speaking, swallowing, or breathing. Symptoms commonly occur on both sides of the body.Īs CMT progresses, you may experience difficulty with a range of voluntary movements.
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